Performance of unanchored matching-adjusted indirect comparison (MAIC) for the evidence synthesis of single-arm trials with time-to-event outcomes

Table 4 Estimates of log hazard ratio in scenario 1 (without effect modifiers)

Statistical properties	Unweighted estimate	Weighted estimate
		All variables included in weight	Omitted menopausal status and tumor grade from weight
Bias	0.164	0.027	0.114
MCV	0.002	0.002	0.002
MSE	0.029	0.003	0.015
CI coverage (%)	11.2	93.8	39.1
mean ESS	NA	791	888

Abbreviation: MCV Monte-Carlo variance; MSE Mean squared error; CI 95% Confidence interval; ESS Effective sample size

ISSN: 1471-2288