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Characteristics
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Total (N = 81)
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Year 2002 (N = 29)
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Year 2012 (N = 52)
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|---|
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Journal characteristics
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Journal Impact Factor, median (IQR)
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4.2 (2.3–6.1)
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4.4 (2.9–5.6)
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3.9 (2.0–6.6)
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General medical journal
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15 (19%)
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5 (17%)
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10 (19%)
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Core clinical journals
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19 (23%)
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9 (31%)
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10 (19%)
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Author characteristics
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Affiliated with industry
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5 (6%)
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3 (10%)
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2 (4%)
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Affiliated with biostatistics or epidemiology department
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35 (43%)
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16 (55%)
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19 (37%)
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Ten or more of studies
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73 (90%)
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26 (90%)
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47 (90%)
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Drug intervention
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38 (47%)
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15 (52%)
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23 (44%)
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Type of outcome in meta-regression analysis
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Binary
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39 (48%)
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13 (45%)
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26 (50%)
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Continuous
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48 (59%)
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18 (62%)
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30 (58%)
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Clinical field
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Psychiatry & Psychology
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13 (16%)
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5 (17%)
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8 (15%)
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Cardiology
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10 (12%)
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3 (10%)
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7 (13%)
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Oncology
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8 (10%)
|
1 (3%)
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7 (13%)
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Infectious disease
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7 (9%)
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2 (7%)
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5 (10%)
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Endocrinology & Metabolism
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7 (9%)
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3 (10%)
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4 (8%)
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Surgery
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6 (7%)
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0 (0%)
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6 (12%)
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General internal medicine
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5 (6%)
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3 (10%)
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2 (4%)
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Paediatrics
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4 (5%)
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2 (7%)
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2 (4%)
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Nutrition & dietetics
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4 (5%)
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0 (0%)
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4 (8%)
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Rheumatology
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4 (5%)
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3 (10%)
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1 (2%)
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Miscellaneous
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13 (16%)
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7 (24%)
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6 (12%)
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- There were no important differences in baseline characteristics between the two assessed years